PTPN4-GRID1 Fusion FISH Probe
The PTPN4-GRID1 Fusion FISH Probe is used to confirm a fusion of the PTPN4 and GRID1 genes. The fusion of the PTPN4 and GRID1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPN4-GRID1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-RERE | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-REOR | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-REGO | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-REGR | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-OROR | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-GORE | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-GROR | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPN4-GRID1-20-AQAQ | 20 (40 μL) | 200 μL |
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GRID1 Gene Summary
This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]
Gene Name: Glutamate Ionotropic Receptor Delta Type Subunit 1
Chromosome: CHR10: 87359311 -88126250
Locus: 10q23.1-q23.2
PTPN4 Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 4
Chromosome: CHR2: 120517206 -120735037
Locus: 2q14.2
Gene Diseases
The PTPN4 GRID1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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