PTPN23-KLHL18 Fusion FISH Probe
The PTPN23-KLHL18 Fusion FISH Probe is used to confirm a fusion of the PTPN23 and KLHL18 genes. The fusion of the PTPN23 and KLHL18 genes has been associated with Lung Adenocarcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPN23-KLHL18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-RERE | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-REOR | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-REGO | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-REGR | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-OROR | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-GORE | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-GROR | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPN23-KLHL18-20-AQAQ | 20 (40 μL) | 200 μL |
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KLHL18 Gene Summary
The Kelch Like Family Member 18 (KLHL18) gene is located on chr3 :47324329-47388306 at 3p21.31.
Gene Name: Kelch Like Family Member 18
Chromosome: CHR3: 47324329 -47388306
Locus: 3p21.31
PTPN23 Gene Summary
This gene encodes a member of the non-receptor type protein-tyrosine phosphatase family. The encoded protein may be involved in the regulation of small nuclear ribonucleo protein assembly and pre-mRNA splicing by modifying the survival motor neuron (SMN) complex. The encoded protein additionally plays a role in ciliogenesis and is part of endosomal sorting complex required for transport (ESCRT) pathways. This gene may serve a tumor suppressor function. [provided by RefSeq, Jul 2016]
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 23
Chromosome: CHR3: 47422490 -47454931
Locus: 3p21.31
Gene Diseases
The PTPN23 KLHL18 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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