PTK7-GNMT Fusion FISH Probe
The PTK7-GNMT Fusion FISH Probe is used to confirm a fusion of the PTK7 and GNMT genes. The fusion of the PTK7 and GNMT genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTK7-GNMT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PTK7-GNMT-20-AQAQ | 20 (40 μL) | 200 μL |
|
PTK7 Gene Summary
This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: Protein Tyrosine Kinase 7 (inactive)
Chromosome: CHR6: 43044028 -43129457
Locus: 6p21.1
GNMT Gene Summary
The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between the upstream CNPY3 (canopy FGF signaling regulator 3) gene and this gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]
Gene Name: Glycine N-methyltransferase
Chromosome: CHR6: 42928499 -42931618
Locus: 6p21.1
Gene Diseases
The PTK7 GNMT Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|