PTK2-PPP2R5E Fusion FISH Probe
The PTK2-PPP2R5E Fusion FISH Probe is used to confirm a fusion of the PTK2 and PPP2R5E genes. The fusion of the PTK2 and PPP2R5E genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTK2-PPP2R5E-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-RERE | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-REOR | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-REGO | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-REGR | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-REAQ | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-ORRE | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-OROR | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-ORGO | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-GORE | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-GOOR | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-GOGO | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-GOGR | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-GRRE | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-GROR | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-GRGO | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-GRGR | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-AQRE | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-AQOR | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-AQGO | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-AQGR | 20 (40 μL) | 200 μL |
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| PTK2-PPP2R5E-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2R5E Gene Summary
The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
Gene Name: Protein Phosphatase 2 Regulatory Subunit B'epsilon
Chromosome: CHR14: 63841354 -64010079
Locus: 14q23.2
PTK2 Gene Summary
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
Gene Name: Protein Tyrosine Kinase 2
Chromosome: CHR8: 141668480 -142011412
Locus: 8q24.3
Gene Diseases
The PTK2 PPP2R5E Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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