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PTK2-DENND3 Fusion FISH Probe

The PTK2-DENND3 Fusion FISH Probe is used to confirm a fusion of the PTK2 and DENND3 genes. The fusion of the PTK2 and DENND3 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PTK2-DENND3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PTK2-DENND3-20-RERE 20 (40 μL) 200 μL
PTK2-DENND3-20-REOR 20 (40 μL) 200 μL
PTK2-DENND3-20-REGO 20 (40 μL) 200 μL
PTK2-DENND3-20-REGR 20 (40 μL) 200 μL
PTK2-DENND3-20-REAQ 20 (40 μL) 200 μL
PTK2-DENND3-20-ORRE 20 (40 μL) 200 μL
PTK2-DENND3-20-OROR 20 (40 μL) 200 μL
PTK2-DENND3-20-ORGO 20 (40 μL) 200 μL
PTK2-DENND3-20-ORAQ 20 (40 μL) 200 μL
PTK2-DENND3-20-GORE 20 (40 μL) 200 μL
PTK2-DENND3-20-GOOR 20 (40 μL) 200 μL
PTK2-DENND3-20-GOGO 20 (40 μL) 200 μL
PTK2-DENND3-20-GOGR 20 (40 μL) 200 μL
PTK2-DENND3-20-GOAQ 20 (40 μL) 200 μL
PTK2-DENND3-20-GRRE 20 (40 μL) 200 μL
PTK2-DENND3-20-GROR 20 (40 μL) 200 μL
PTK2-DENND3-20-GRGO 20 (40 μL) 200 μL
PTK2-DENND3-20-GRGR 20 (40 μL) 200 μL
PTK2-DENND3-20-GRAQ 20 (40 μL) 200 μL
PTK2-DENND3-20-AQRE 20 (40 μL) 200 μL
PTK2-DENND3-20-AQOR 20 (40 μL) 200 μL
PTK2-DENND3-20-AQGO 20 (40 μL) 200 μL
PTK2-DENND3-20-AQGR 20 (40 μL) 200 μL
PTK2-DENND3-20-AQAQ 20 (40 μL) 200 μL

PTK2 Gene Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]

Gene Name: Protein Tyrosine Kinase 2

Chromosome: CHR8: 141668480 -142011412

Locus: 8q24.3

DENND3 Gene Summary

The DENN Domain Containing 3 (DENND3) gene is located on chr8 :142138719-142205900 at 8q24.3.

Gene Name: DENN Domain Containing 3

Chromosome: CHR8: 142138719 -142205900

Locus: 8q24.3

Gene Diseases

The PTK2 DENND3 Fusion has been associated with the following diseases:

Disease Name
Stomach Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.