PTK2-CACNG8 Fusion FISH Probe
The PTK2-CACNG8 Fusion FISH Probe is used to confirm a fusion of the PTK2 and CACNG8 genes. The fusion of the PTK2 and CACNG8 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTK2-CACNG8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PTK2-CACNG8-20-AQAQ | 20 (40 μL) | 200 μL |
|
PTK2 Gene Summary
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
Gene Name: Protein Tyrosine Kinase 2
Chromosome: CHR8: 141668480 -142011412
Locus: 8q24.3
CACNG8 Gene Summary
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. The mRNA for this gene is believed to initiate translation from a non-AUG (CUG) start codon. [provided by RefSeq, Dec 2010]
Gene Name: Calcium Voltage-gated Channel Auxiliary Subunit Gamma 8
Chromosome: CHR19: 54466289 -54493469
Locus: 19q13.42
Gene Diseases
The PTK2 CACNG8 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|