PTK2-ANKRD11 Fusion FISH Probe
The PTK2-ANKRD11 Fusion FISH Probe is used to confirm a fusion of the PTK2 and ANKRD11 genes. The fusion of the PTK2 and ANKRD11 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTK2-ANKRD11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-RERE | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-REOR | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-REGO | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-REGR | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-REAQ | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-ORRE | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-OROR | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-ORGO | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-GORE | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-GOOR | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-GOGO | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-GOGR | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-GRRE | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-GROR | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-GRGO | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-GRGR | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-AQRE | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-AQOR | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-AQGO | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-AQGR | 20 (40 μL) | 200 μL |
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| PTK2-ANKRD11-20-AQAQ | 20 (40 μL) | 200 μL |
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PTK2 Gene Summary
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
Gene Name: Protein Tyrosine Kinase 2
Chromosome: CHR8: 141668480 -142011412
Locus: 8q24.3
ANKRD11 Gene Summary
This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012]
Gene Name: Ankyrin Repeat Domain 11
Chromosome: CHR16: 89334034 -89556969
Locus: 16q24.3
Gene Diseases
The PTK2 ANKRD11 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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