PTGDS-EEA1 Fusion FISH Probe
The PTGDS-EEA1 Fusion FISH Probe is used to confirm a fusion of the PTGDS and EEA1 genes. The fusion of the PTGDS and EEA1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTGDS-EEA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-RERE | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-REOR | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-REGO | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-REGR | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-REAQ | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-ORRE | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-OROR | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-ORGO | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-GORE | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-GOOR | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-GOGO | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-GOGR | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-GRRE | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-GROR | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-GRGO | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-GRGR | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-AQRE | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-AQOR | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-AQGO | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-AQGR | 20 (40 μL) | 200 μL |
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| PTGDS-EEA1-20-AQAQ | 20 (40 μL) | 200 μL |
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PTGDS Gene Summary
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008]
Gene Name: Prostaglandin D2 Synthase
Chromosome: CHR9: 139871955 -139876194
Locus: 9q34.3
EEA1 Gene Summary
The Early Endosome Antigen 1 (EEA1) gene is located on chr12 :93166284-93323107 at 12q22.
Gene Name: Early Endosome Antigen 1
Chromosome: CHR12: 93166284 -93323107
Locus: 12q22
Gene Diseases
The PTGDS EEA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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