PSMD11-DPRX Fusion FISH Probe
The PSMD11-DPRX Fusion FISH Probe is used to confirm a fusion of the PSMD11 and DPRX genes. The fusion of the PSMD11 and DPRX genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PSMD11-DPRX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PSMD11-DPRX-20-AQAQ | 20 (40 μL) | 200 μL |
|
PSMD11 Gene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: Proteasome 26S Subunit, Non-ATPase 11
Chromosome: CHR17: 30771501 -30808042
Locus: 17q11.2
DPRX Gene Summary
Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the DPRX homeobox gene family. Evidence of mRNA expression has not yet been found for this gene. Multiple, related processed pseudogenes have been found which are thought to reflect expression of this gene in the germ line or embryonic cells. [provided by RefSeq, Jul 2008]
Gene Name: Divergent-paired Related Homeobox
Chromosome: CHR19: 54135309 -54140263
Locus: 19q13.42
Gene Diseases
The PSMD11 DPRX Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|