PSMB7-NR6A1 Fusion FISH Probe
The PSMB7-NR6A1 Fusion FISH Probe is used to confirm a fusion of the PSMB7 and NR6A1 genes. The fusion of the PSMB7 and NR6A1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PSMB7-NR6A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-RERE | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-REOR | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-REGO | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-REGR | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-REAQ | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-ORRE | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-OROR | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-ORGO | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-GORE | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-GOOR | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-GOGO | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-GOGR | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-GRRE | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-GROR | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-GRGO | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-GRGR | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-AQRE | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-AQOR | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-AQGO | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-AQGR | 20 (40 μL) | 200 μL |
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| PSMB7-NR6A1-20-AQAQ | 20 (40 μL) | 200 μL |
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NR6A1 Gene Summary
This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2013]
Gene Name: Nuclear Receptor Subfamily 6 Group A Member 1
Chromosome: CHR9: 127284702 -127533576
Locus: 9q33.3
PSMB7 Gene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Jul 2012]
Gene Name: Proteasome Subunit Beta 7
Chromosome: CHR9: 127115743 -127177721
Locus: 9q33.3
Gene Diseases
The PSMB7 NR6A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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