PSMB2-FAM116B Fusion FISH Probe
The PSMB2-FAM116B Fusion FISH Probe is used to confirm a fusion of the PSMB2 and FAM116B genes. The fusion of the PSMB2 and FAM116B genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PSMB2-FAM116B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-RERE | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-REOR | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-REGO | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-REGR | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-REAQ | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-ORRE | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-OROR | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-ORGO | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-GORE | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-GOOR | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-GOGO | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-GOGR | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-GRRE | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-GROR | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-GRGO | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-GRGR | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-AQRE | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-AQOR | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-AQGO | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-AQGR | 20 (40 μL) | 200 μL |
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| PSMB2-FAM116B-20-AQAQ | 20 (40 μL) | 200 μL |
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PSMB2 Gene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Proteasome Subunit Beta 2
Chromosome: CHR1: 36065142 -36107445
Locus: 1p34.3
Gene Diseases
The PSMB2 FAM116B Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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