PSMA5-FOXP1 Fusion FISH Probe
The PSMA5-FOXP1 Fusion FISH Probe is used to confirm a fusion of the PSMA5 and FOXP1 genes. The fusion of the PSMA5 and FOXP1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PSMA5-FOXP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-RERE | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-REOR | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-REGO | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-REGR | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-REAQ | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-ORRE | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-OROR | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-ORGO | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-GORE | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-GOOR | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-GOGO | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-GOGR | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-GRRE | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-GROR | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-GRGO | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-GRGR | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-AQRE | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-AQOR | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-AQGO | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-AQGR | 20 (40 μL) | 200 μL |
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| PSMA5-FOXP1-20-AQAQ | 20 (40 μL) | 200 μL |
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PSMA5 Gene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Proteasome Subunit Alpha 5
Chromosome: CHR1: 109941652 -109969108
Locus: 1p13.3
FOXP1 Gene Summary
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box P1
Chromosome: CHR3: 71004735 -71633140
Locus: 3p13
Gene Diseases
The PSMA5 FOXP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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