PSAP-TCERG1 Fusion FISH Probe
The PSAP-TCERG1 Fusion FISH Probe is used to confirm a fusion of the PSAP and TCERG1 genes. The fusion of the PSAP and TCERG1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PSAP-TCERG1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-RERE | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-REOR | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-REGO | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-REGR | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-REAQ | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-ORRE | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-OROR | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-ORGO | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-GORE | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-GOOR | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-GOGO | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-GOGR | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-GRRE | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-GROR | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-GRGO | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-GRGR | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-AQRE | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-AQOR | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-AQGO | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-AQGR | 20 (40 μL) | 200 μL |
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| PSAP-TCERG1-20-AQAQ | 20 (40 μL) | 200 μL |
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PSAP Gene Summary
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Gene Name: Prosaposin
Chromosome: CHR10: 73576054 -73611082
Locus: 10q22.1
TCERG1 Gene Summary
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Transcription Elongation Regulator 1
Chromosome: CHR5: 145826872 -145891069
Locus: 5q32
Gene Diseases
The PSAP TCERG1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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