PRX-BLVRB Fusion FISH Probe
The PRX-BLVRB Fusion FISH Probe is used to confirm a fusion of the PRX and BLVRB genes. The fusion of the PRX and BLVRB genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRX-BLVRB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-RERE | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-REOR | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-REGO | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-REGR | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-REAQ | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-ORRE | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-OROR | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-ORGO | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-GORE | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-GOOR | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-GOGO | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-GOGR | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-GRRE | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-GROR | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-GRGO | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-GRGR | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-AQRE | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-AQOR | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-AQGO | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-AQGR | 20 (40 μL) | 200 μL |
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| PRX-BLVRB-20-AQAQ | 20 (40 μL) | 200 μL |
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BLVRB Gene Summary
The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM, Jul 2009]
Gene Name: Biliverdin Reductase B
Chromosome: CHR19: 40953690 -40971725
Locus: 19q13.2
PRX Gene Summary
This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. [provided by RefSeq, Jul 2008]
Gene Name: Periaxin
Chromosome: CHR19: 40899670 -40919271
Locus: 19q13.2
Gene Diseases
The PRX BLVRB Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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