PRRG2-FCGRT Fusion FISH Probe
The PRRG2-FCGRT Fusion FISH Probe is used to confirm a fusion of the PRRG2 and FCGRT genes. The fusion of the PRRG2 and FCGRT genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRRG2-FCGRT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-RERE | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-REOR | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-REGO | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-REGR | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-REAQ | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-ORRE | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-OROR | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-ORGO | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-GORE | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-GOOR | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-GOGO | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-GOGR | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-GRRE | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-GROR | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-GRGO | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-GRGR | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-AQRE | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-AQOR | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-AQGO | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-AQGR | 20 (40 μL) | 200 μL |
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| PRRG2-FCGRT-20-AQAQ | 20 (40 μL) | 200 μL |
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FCGRT Gene Summary
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Gene Name: Fc Fragment Of IgG Receptor And Transporter
Chromosome: CHR19: 50015535 -50029685
Locus: 19q13.33
PRRG2 Gene Summary
The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Name: Proline Rich And Gla Domain 2
Chromosome: CHR19: 50084586 -50094265
Locus: 19q13.33
Gene Diseases
The PRRG2 FCGRT Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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