PRRG2-AGPAT2 Fusion FISH Probe
The PRRG2-AGPAT2 Fusion FISH Probe is used to confirm a fusion of the PRRG2 and AGPAT2 genes. The fusion of the PRRG2 and AGPAT2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRRG2-AGPAT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-RERE | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-REOR | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-REGO | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-REGR | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-REAQ | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-ORRE | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-OROR | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-ORGO | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-GORE | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-GOOR | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-GOGO | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-GOGR | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-GRRE | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-GROR | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-GRGO | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-GRGR | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-AQRE | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-AQOR | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-AQGO | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-AQGR | 20 (40 μL) | 200 μL |
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| PRRG2-AGPAT2-20-AQAQ | 20 (40 μL) | 200 μL |
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PRRG2 Gene Summary
The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Name: Proline Rich And Gla Domain 2
Chromosome: CHR19: 50084586 -50094265
Locus: 19q13.33
AGPAT2 Gene Summary
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: 1-acylglycerol-3-phosphate O-acyltransferase 2
Chromosome: CHR9: 139567594 -139581911
Locus: 9q34.3
Gene Diseases
The PRRG2 AGPAT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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