PRR15L-CBX1 Fusion FISH Probe
The PRR15L-CBX1 Fusion FISH Probe is used to confirm a fusion of the PRR15L and CBX1 genes. The fusion of the PRR15L and CBX1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRR15L-CBX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-RERE | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-REOR | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-REGO | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-REGR | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-REAQ | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-ORRE | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-OROR | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-ORGO | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-GORE | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-GOOR | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-GOGO | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-GOGR | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-GRRE | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-GROR | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-GRGO | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-GRGR | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-AQRE | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-AQOR | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-AQGO | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-AQGR | 20 (40 μL) | 200 μL |
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| PRR15L-CBX1-20-AQAQ | 20 (40 μL) | 200 μL |
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CBX1 Gene Summary
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Chromobox 1
Chromosome: CHR17: 46147413 -46178883
Locus: 17q21.32
PRR15L Gene Summary
The Proline Rich 15 Like (PRR15L) gene is located on chr17 :46029333-46035110 at 17q21.32.
Gene Name: Proline Rich 15 Like
Chromosome: CHR17: 46029333 -46035110
Locus: 17q21.32
Gene Diseases
The PRR15L CBX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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