PRPF6-DNAJC5 Fusion FISH Probe
The PRPF6-DNAJC5 Fusion FISH Probe is used to confirm a fusion of the PRPF6 and DNAJC5 genes. The fusion of the PRPF6 and DNAJC5 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRPF6-DNAJC5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-RERE | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-REOR | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-REGO | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-REGR | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-REAQ | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-ORRE | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-OROR | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-ORGO | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-GORE | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-GOOR | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-GOGO | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-GOGR | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-GRRE | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-GROR | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-GRGO | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-GRGR | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-AQRE | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-AQOR | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-AQGO | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-AQGR | 20 (40 μL) | 200 μL |
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| PRPF6-DNAJC5-20-AQAQ | 20 (40 μL) | 200 μL |
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PRPF6 Gene Summary
The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing. [provided by RefSeq, Jul 2008]
Gene Name: Pre-mRNA Processing Factor 6
Chromosome: CHR20: 62612430 -62664453
Locus: 20q13.33
DNAJC5 Gene Summary
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C5
Chromosome: CHR20: 62526454 -62567384
Locus: 20q13.33
Gene Diseases
The PRPF6 DNAJC5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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