PRPF4B-FAM50B Fusion FISH Probe
The PRPF4B-FAM50B Fusion FISH Probe is used to confirm a fusion of the PRPF4B and FAM50B genes. The fusion of the PRPF4B and FAM50B genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRPF4B-FAM50B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-RERE | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-REOR | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-REGO | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-REGR | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-REAQ | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-ORRE | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-OROR | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-ORGO | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-GORE | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-GOOR | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-GOGO | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-GOGR | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-GRRE | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-GROR | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-GRGO | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-GRGR | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-AQRE | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-AQOR | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-AQGO | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-AQGR | 20 (40 μL) | 200 μL |
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| PRPF4B-FAM50B-20-AQAQ | 20 (40 μL) | 200 μL |
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PRPF4B Gene Summary
Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]
Gene Name: Pre-mRNA Processing Factor 4B
Chromosome: CHR6: 4021568 -4065217
Locus: 6p25.2
FAM50B Gene Summary
This gene contains an intronless ORF that arose from ancestral retroposition. The encoded protein is related to a plant protein that plays a role in the circadian clock. This gene is adjacent to a differentially methylated region (DMR) and is imprinted and paternally expressed in many tissues. [provided by RefSeq, Nov 2015]
Gene Name: Family With Sequence Similarity 50 Member B
Chromosome: CHR6: 3849631 -3851551
Locus: 6p25.2
Gene Diseases
The PRPF4B FAM50B Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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