PRPF19-NLRP14 Fusion FISH Probe
The PRPF19-NLRP14 Fusion FISH Probe is used to confirm a fusion of the PRPF19 and NLRP14 genes. The fusion of the PRPF19 and NLRP14 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRPF19-NLRP14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-RERE | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-REOR | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-REGO | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-REGR | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-REAQ | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-ORRE | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-OROR | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-ORGO | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-GORE | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-GOOR | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-GOGO | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-GOGR | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-GRRE | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-GROR | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-GRGO | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-GRGR | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-AQRE | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-AQOR | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-AQGO | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-AQGR | 20 (40 μL) | 200 μL |
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| PRPF19-NLRP14-20-AQAQ | 20 (40 μL) | 200 μL |
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PRPF19 Gene Summary
PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair (Beck et al., 2008 [PubMed 18263876]).[supplied by OMIM, Sep 2008]
Gene Name: Pre-mRNA Processing Factor 19
Chromosome: CHR11: 60658019 -60674061
Locus: 11q12.2
NLRP14 Gene Summary
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]
Gene Name: NLR Family Pyrin Domain Containing 14
Chromosome: CHR11: 7041699 -7092757
Locus: 11p15.4
Gene Diseases
The PRPF19 NLRP14 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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