PRPF18-CCDC3 Fusion FISH Probe
The PRPF18-CCDC3 Fusion FISH Probe is used to confirm a fusion of the PRPF18 and CCDC3 genes. The fusion of the PRPF18 and CCDC3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRPF18-CCDC3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-RERE | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-REOR | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-REGO | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-REGR | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-REAQ | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-ORRE | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-OROR | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-ORGO | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-GORE | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-GOOR | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-GOGO | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-GOGR | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-GRRE | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-GROR | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-GRGO | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-GRGR | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-AQRE | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-AQOR | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-AQGO | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-AQGR | 20 (40 μL) | 200 μL |
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| PRPF18-CCDC3-20-AQAQ | 20 (40 μL) | 200 μL |
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PRPF18 Gene Summary
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]
Gene Name: Pre-mRNA Processing Factor 18
Chromosome: CHR10: 13628938 -13672868
Locus: 10p13
CCDC3 Gene Summary
The Coiled-coil Domain Containing 3 (CCDC3) gene is located on chr10 :12938624-13043704 at 10p13.
Gene Name: Coiled-coil Domain Containing 3
Chromosome: CHR10: 12938624 -13043704
Locus: 10p13
Gene Diseases
The PRPF18 CCDC3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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