PRMT7-NFATC3 Fusion FISH Probe
The PRMT7-NFATC3 Fusion FISH Probe is used to confirm a fusion of the PRMT7 and NFATC3 genes. The fusion of the PRMT7 and NFATC3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRMT7-NFATC3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-RERE | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-REOR | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-REGO | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-REGR | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-REAQ | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-ORRE | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-OROR | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-ORGO | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-GORE | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-GOOR | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-GOGO | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-GOGR | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-GRRE | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-GROR | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-GRGO | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-GRGR | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-AQRE | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-AQOR | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-AQGO | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-AQGR | 20 (40 μL) | 200 μL |
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| PRMT7-NFATC3-20-AQAQ | 20 (40 μL) | 200 μL |
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NFATC3 Gene Summary
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010]
Gene Name: Nuclear Factor Of Activated T-cells 3
Chromosome: CHR16: 68119268 -68263162
Locus: 16q22.1
PRMT7 Gene Summary
This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients. [provided by RefSeq, May 2017]
Gene Name: Protein Arginine Methyltransferase 7
Chromosome: CHR16: 68344876 -68391169
Locus: 16q22.1
Gene Diseases
The PRMT7 NFATC3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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