PRMT2-WRB Fusion FISH Probe
The PRMT2-WRB Fusion FISH Probe is used to confirm a fusion of the PRMT2 and WRB genes. The fusion of the PRMT2 and WRB genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRMT2-WRB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-RERE | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-REOR | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-REGO | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-REGR | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-REAQ | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-ORRE | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-OROR | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-ORGO | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-GORE | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-GOOR | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-GOGO | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-GOGR | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-GRRE | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-GROR | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-GRGO | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-GRGR | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-AQRE | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-AQOR | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-AQGO | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-AQGR | 20 (40 μL) | 200 μL |
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| PRMT2-WRB-20-AQAQ | 20 (40 μL) | 200 μL |
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PRMT2 Gene Summary
The Protein Arginine Methyltransferase 2 (PRMT2) gene is located on chr21 :48055506-48085155 at 21q22.3.
Gene Name: Protein Arginine Methyltransferase 2
Chromosome: CHR21: 48055506 -48085155
Locus: 21q22.3
WRB Gene Summary
This gene is located in the candidate region for congenital heart disease (CHD) in Down syndrome (DS). It encodes a basic protein that functions as a receptor that promotes insertion of tail-anchored proteins in the endoplasmic reticulum membrane. This gene is located at a maternally-methylated differentially methylated region (DMR); however, its transcription may be biallelic, not imprinted. Alternative splicing results in different transcript variants. A pseudogene has been defined on chromosome 4. [provided by RefSeq, Apr 2017]
Gene Name: Tryptophan Rich Basic Protein
Chromosome: CHR21: 40752212 -40769815
Locus: 21q22.2
Gene Diseases
The PRMT2 WRB Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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