PRLR-KDM3B Fusion FISH Probe
The PRLR-KDM3B Fusion FISH Probe is used to confirm a fusion of the PRLR and KDM3B genes. The fusion of the PRLR and KDM3B genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRLR-KDM3B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-RERE | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-REOR | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-REGO | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-REGR | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-REAQ | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-ORRE | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-OROR | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-ORGO | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-GORE | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-GOOR | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-GOGO | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-GOGR | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-GRRE | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-GROR | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-GRGO | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-GRGR | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-AQRE | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-AQOR | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-AQGO | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-AQGR | 20 (40 μL) | 200 μL |
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| PRLR-KDM3B-20-AQAQ | 20 (40 μL) | 200 μL |
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PRLR Gene Summary
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
Gene Name: Prolactin Receptor
Chromosome: CHR5: 35055801 -35230823
Locus: 5p13.2
KDM3B Gene Summary
The Lysine Demethylase 3B (KDM3B) gene is located on chr5 :137688284-137772716 at 5q31.2.
Gene Name: Lysine Demethylase 3B
Chromosome: CHR5: 137688284 -137772716
Locus: 5q31.2
Gene Diseases
The PRLR KDM3B Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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