PRLR-CLPTM1L Fusion FISH Probe
The PRLR-CLPTM1L Fusion FISH Probe is used to confirm a fusion of the PRLR and CLPTM1L genes. The fusion of the PRLR and CLPTM1L genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRLR-CLPTM1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-RERE | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-REOR | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-REGO | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-REGR | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-REAQ | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-ORRE | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-OROR | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-ORGO | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-GORE | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-GOOR | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-GOGO | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-GOGR | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-GRRE | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-GROR | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-GRGO | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-GRGR | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-AQRE | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-AQOR | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-AQGO | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-AQGR | 20 (40 μL) | 200 μL |
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| PRLR-CLPTM1L-20-AQAQ | 20 (40 μL) | 200 μL |
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PRLR Gene Summary
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
Gene Name: Prolactin Receptor
Chromosome: CHR5: 35055801 -35230823
Locus: 5p13.2
CLPTM1L Gene Summary
The protein encoded by this gene is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in this gene have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. [provided by RefSeq, Nov 2015]
Gene Name: CLPTM1 Like
Chromosome: CHR5: 1317999 -1345002
Locus: 5p15.33
Gene Diseases
The PRLR CLPTM1L Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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