PRKRA-SEC31A Fusion FISH Probe
The PRKRA-SEC31A Fusion FISH Probe is used to confirm a fusion of the PRKRA and SEC31A genes. The fusion of the PRKRA and SEC31A genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRKRA-SEC31A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-RERE | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-REOR | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-REGO | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-REGR | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-REAQ | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-ORRE | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-OROR | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-ORGO | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-GORE | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-GOOR | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-GOGO | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-GOGR | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-GRRE | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-GROR | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-GRGO | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-GRGR | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-AQRE | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-AQOR | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-AQGO | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-AQGR | 20 (40 μL) | 200 μL |
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| PRKRA-SEC31A-20-AQAQ | 20 (40 μL) | 200 μL |
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PRKRA Gene Summary
This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
Gene Name: Protein Activator Of Interferon Induced Protein Kinase EIF2AK2
Chromosome: CHR2: 179296140 -179315958
Locus: 2q31.2
SEC31A Gene Summary
The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Name: SEC31 Homolog A, COPII Coat Complex Component
Chromosome: CHR4: 83739813 -83812419
Locus: 4q21.22
Gene Diseases
The PRKRA SEC31A Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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