PRKDC-MYO5A Fusion FISH Probe
The PRKDC-MYO5A Fusion FISH Probe is used to confirm a fusion of the PRKDC and MYO5A genes. The fusion of the PRKDC and MYO5A genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRKDC-MYO5A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-RERE | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-REOR | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-REGO | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-REGR | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-REAQ | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-ORRE | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-OROR | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-ORGO | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-GORE | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-GOOR | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-GOGO | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-GOGR | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-GRRE | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-GROR | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-GRGO | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-GRGR | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-AQRE | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-AQOR | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-AQGO | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-AQGR | 20 (40 μL) | 200 μL |
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| PRKDC-MYO5A-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO5A Gene Summary
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined. [provided by RefSeq, Dec 2008]
Gene Name: Myosin VA
Chromosome: CHR15: 52599479 -52821247
Locus: 15q21.2
PRKDC Gene Summary
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
Gene Name: Protein Kinase, DNA-activated, Catalytic Polypeptide
Chromosome: CHR8: 48685668 -48872743
Locus: 8q11.21
Gene Diseases
The PRKDC MYO5A Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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