PRKD2-MYH14 Fusion FISH Probe
The PRKD2-MYH14 Fusion FISH Probe is used to confirm a fusion of the PRKD2 and MYH14 genes. The fusion of the PRKD2 and MYH14 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRKD2-MYH14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-RERE | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-REOR | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-REGO | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-REGR | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-REAQ | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-ORRE | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-OROR | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-ORGO | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-GORE | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-GOOR | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-GOGO | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-GOGR | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-GRRE | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-GROR | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-GRGO | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-GRGR | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-AQRE | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-AQOR | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-AQGO | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-AQGR | 20 (40 μL) | 200 μL |
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| PRKD2-MYH14-20-AQAQ | 20 (40 μL) | 200 μL |
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PRKD2 Gene Summary
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Protein Kinase D2
Chromosome: CHR19: 47177572 -47220384
Locus: 19q13.32
MYH14 Gene Summary
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Heavy Chain 14
Chromosome: CHR19: 50706884 -50813801
Locus: 19q13.33
Gene Diseases
The PRKD2 MYH14 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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