PRKD2-CKM Fusion FISH Probe
The PRKD2-CKM Fusion FISH Probe is used to confirm a fusion of the PRKD2 and CKM genes. The fusion of the PRKD2 and CKM genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRKD2-CKM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-RERE | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-REOR | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-REGO | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-REGR | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-REAQ | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-ORRE | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-OROR | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-ORGO | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-GORE | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-GOOR | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-GOGO | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-GOGR | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-GRRE | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-GROR | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-GRGO | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-GRGR | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-AQRE | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-AQOR | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-AQGO | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-AQGR | 20 (40 μL) | 200 μL |
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| PRKD2-CKM-20-AQAQ | 20 (40 μL) | 200 μL |
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CKM Gene Summary
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]
Gene Name: Creatine Kinase, M-type
Chromosome: CHR19: 45809670 -45826233
Locus: 19q13.32
PRKD2 Gene Summary
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Protein Kinase D2
Chromosome: CHR19: 47177572 -47220384
Locus: 19q13.32
Gene Diseases
The PRKD2 CKM Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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