PRKCE-QPCT Fusion FISH Probe
The PRKCE-QPCT Fusion FISH Probe is used to confirm a fusion of the PRKCE and QPCT genes. The fusion of the PRKCE and QPCT genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRKCE-QPCT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PRKCE-QPCT-20-AQAQ | 20 (40 μL) | 200 μL |
|
PRKCE Gene Summary
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
Gene Name: Protein Kinase C Epsilon
Chromosome: CHR2: 45879042 -46415129
Locus: 2p21
QPCT Gene Summary
This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008]
Gene Name: Glutaminyl-peptide Cyclotransferase
Chromosome: CHR2: 37571752 -37600465
Locus: 2p22.2
Gene Diseases
The PRKCE QPCT Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|