PRKCA-SDK1 Fusion FISH Probe
The PRKCA-SDK1 Fusion FISH Probe is used to confirm a fusion of the PRKCA and SDK1 genes. The fusion of the PRKCA and SDK1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRKCA-SDK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-RERE | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-REOR | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-REGO | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-REGR | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-REAQ | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-ORRE | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-OROR | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-ORGO | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-GORE | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-GOOR | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-GOGO | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-GOGR | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-GRRE | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-GROR | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-GRGO | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-GRGR | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-AQRE | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-AQOR | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-AQGO | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-AQGR | 20 (40 μL) | 200 μL |
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| PRKCA-SDK1-20-AQAQ | 20 (40 μL) | 200 μL |
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PRKCA Gene Summary
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
Gene Name: Protein Kinase C Alpha
Chromosome: CHR17: 64298925 -64806862
Locus: 17q24.2
SDK1 Gene Summary
The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains six immunoglobulin-like domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Gene Name: Sidekick Cell Adhesion Molecule 1
Chromosome: CHR7: 3341079 -4308631
Locus: 7p22.2
Gene Diseases
The PRKCA SDK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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