PRKCA-PI4KA Fusion FISH Probe
The PRKCA-PI4KA Fusion FISH Probe is used to confirm a fusion of the PRKCA and PI4KA genes. The fusion of the PRKCA and PI4KA genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRKCA-PI4KA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-RERE | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-REOR | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-REGO | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-REGR | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-REAQ | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-ORRE | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-OROR | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-ORGO | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-GORE | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-GOOR | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-GOGO | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-GOGR | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-GRRE | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-GROR | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-GRGO | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-GRGR | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-AQRE | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-AQOR | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-AQGO | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-AQGR | 20 (40 μL) | 200 μL |
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| PRKCA-PI4KA-20-AQAQ | 20 (40 μL) | 200 μL |
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PI4KA Gene Summary
This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. [provided by RefSeq, Sep 2014]
Gene Name: Phosphatidylinositol 4-kinase Alpha
Chromosome: CHR22: 21061978 -21213070
Locus: 22q11.21
PRKCA Gene Summary
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
Gene Name: Protein Kinase C Alpha
Chromosome: CHR17: 64298925 -64806862
Locus: 17q24.2
Gene Diseases
The PRKCA PI4KA Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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