PRKAG2-MLL3 Fusion FISH Probe
The PRKAG2-MLL3 Fusion FISH Probe is used to confirm a fusion of the PRKAG2 and MLL3 genes. The fusion of the PRKAG2 and MLL3 genes has been associated with Breast Invasive Carcinoma, Prostate Adenocarcinoma, and Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRKAG2-MLL3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-RERE | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-REOR | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-REGO | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-REGR | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-REAQ | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-ORRE | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-OROR | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-ORGO | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-GORE | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-GOOR | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-GOGO | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-GOGR | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-GRRE | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-GROR | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-GRGO | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-GRGR | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-AQRE | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-AQOR | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-AQGO | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-AQGR | 20 (40 μL) | 200 μL |
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| PRKAG2-MLL3-20-AQAQ | 20 (40 μL) | 200 μL |
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PRKAG2 Gene Summary
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2015]
Gene Name: Protein Kinase AMP-activated Non-catalytic Subunit Gamma 2
Chromosome: CHR7: 151253200 -151574316
Locus: 7q36.1
Gene Diseases
The PRKAG2 MLL3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Prostate Adenocarcinoma |
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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