PRICKLE1-LRIG3 Fusion FISH Probe
The PRICKLE1-LRIG3 Fusion FISH Probe is used to confirm a fusion of the PRICKLE1 and LRIG3 genes. The fusion of the PRICKLE1 and LRIG3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRICKLE1-LRIG3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-RERE | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-REOR | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-REGO | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-REGR | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-REAQ | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-ORRE | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-OROR | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-ORGO | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-GORE | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-GOOR | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-GOGO | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-GOGR | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-GRRE | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-GROR | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-GRGO | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-GRGR | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-AQRE | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-AQOR | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-AQGO | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-AQGR | 20 (40 μL) | 200 μL |
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| PRICKLE1-LRIG3-20-AQAQ | 20 (40 μL) | 200 μL |
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LRIG3 Gene Summary
The Leucine Rich Repeats And Immunoglobulin Like Domains 3 (LRIG3) gene is located on chr12 :59265936-59314262 at 12q14.1.
Gene Name: Leucine Rich Repeats And Immunoglobulin Like Domains 3
Chromosome: CHR12: 59265936 -59314262
Locus: 12q14.1
PRICKLE1 Gene Summary
This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]
Gene Name: Prickle Planar Cell Polarity Protein 1
Chromosome: CHR12: 42852139 -42983572
Locus: 12q12
Gene Diseases
The PRICKLE1 LRIG3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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