PREX1-EHBP1 Fusion FISH Probe
The PREX1-EHBP1 Fusion FISH Probe is used to confirm a fusion of the PREX1 and EHBP1 genes. The fusion of the PREX1 and EHBP1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PREX1-EHBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-RERE | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-REOR | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-REGO | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-REGR | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-OROR | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-GORE | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-GROR | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| PREX1-EHBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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EHBP1 Gene Summary
This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Gene Name: EH Domain Binding Protein 1
Chromosome: CHR2: 62900985 -63273621
Locus: 2p15
PREX1 Gene Summary
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008]
Gene Name: Phosphatidylinositol-3,4,5-trisphosphate Dependent Rac Exchange Factor 1
Chromosome: CHR20: 47240792 -47444420
Locus: 20q13.13
Gene Diseases
The PREX1 EHBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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