PREP-ATG5 Fusion FISH Probe
The PREP-ATG5 Fusion FISH Probe is used to confirm a fusion of the PREP and ATG5 genes. The fusion of the PREP and ATG5 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PREP-ATG5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-RERE | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-REOR | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-REGO | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-REGR | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-REAQ | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-ORRE | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-OROR | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-ORGO | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-ORAQ | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-GORE | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-GOOR | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-GOGO | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-GOGR | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-GOAQ | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-GRRE | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-GROR | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-GRGO | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-GRGR | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-GRAQ | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-AQRE | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-AQOR | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-AQGO | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-AQGR | 20 (40 μL) | 200 μL |
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| PREP-ATG5-20-AQAQ | 20 (40 μL) | 200 μL |
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PREP Gene Summary
The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides. [provided by RefSeq, Jul 2008]
Gene Name: Prolyl Endopeptidase
Chromosome: CHR6: 105725441 -105850999
Locus: 6q21
ATG5 Gene Summary
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Gene Name: Autophagy Related 5
Chromosome: CHR6: 106632351 -106773695
Locus: 6q21
Gene Diseases
The PREP ATG5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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