PRDX1-DDX27 Fusion FISH Probe
The PRDX1-DDX27 Fusion FISH Probe is used to confirm a fusion of the PRDX1 and DDX27 genes. The fusion of the PRDX1 and DDX27 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRDX1-DDX27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-RERE | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-REOR | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-REGO | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-REGR | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-REAQ | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-ORRE | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-OROR | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-ORGO | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-GORE | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-GOOR | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-GOGO | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-GOGR | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-GRRE | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-GROR | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-GRGO | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-GRGR | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-AQRE | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-AQOR | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-AQGO | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-AQGR | 20 (40 μL) | 200 μL |
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| PRDX1-DDX27-20-AQAQ | 20 (40 μL) | 200 μL |
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PRDX1 Gene Summary
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]
Gene Name: Peroxiredoxin 1
Chromosome: CHR1: 45976706 -45988562
Locus: 1p34.1
DDX27 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]
Gene Name: DEAD-box Helicase 27
Chromosome: CHR20: 47835831 -47860614
Locus: 20q13.13
Gene Diseases
The PRDX1 DDX27 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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