PRDM6-NIPAL4 Fusion FISH Probe
The PRDM6-NIPAL4 Fusion FISH Probe is used to confirm a fusion of the PRDM6 and NIPAL4 genes. The fusion of the PRDM6 and NIPAL4 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRDM6-NIPAL4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-RERE | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-REOR | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-REGO | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-REGR | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-REAQ | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-ORRE | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-OROR | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-ORGO | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-GORE | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-GOOR | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-GOGO | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-GOGR | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-GRRE | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-GROR | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-GRGO | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-GRGR | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-AQRE | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-AQOR | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-AQGO | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-AQGR | 20 (40 μL) | 200 μL |
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| PRDM6-NIPAL4-20-AQAQ | 20 (40 μL) | 200 μL |
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PRDM6 Gene Summary
The protein encoded by this gene is a transcriptional repressor and a member of the PRDM family. Family members contain a PR domain and multiple zinc-finger domains. The encoded protein is involved in regulation of vascular smooth muscle cells (VSMC) contractile proteins. Mutations in this gene result in patent ductus arteriosus 3 (PDA3). [provided by RefSeq, Apr 2017]
Gene Name: PR/SET Domain 6
Chromosome: CHR5: 122424840 -122523745
Locus: 5q23.2
NIPAL4 Gene Summary
This gene likely encodes a membrane receptor. Mutations in this gene have been associated with autosomal recessive congenital ichthyosis. [provided by RefSeq, Feb 2010]
Gene Name: NIPA Like Domain Containing 4
Chromosome: CHR5: 156887026 -156901730
Locus: 5q33.3
Gene Diseases
The PRDM6 NIPAL4 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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