PRCC-RHBG Fusion FISH Probe
The PRCC-RHBG Fusion FISH Probe is used to confirm a fusion of the PRCC and RHBG genes. The fusion of the PRCC and RHBG genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRCC-RHBG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-RERE | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-REOR | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-REGO | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-REGR | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-REAQ | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-ORRE | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-OROR | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-ORGO | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-GORE | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-GOOR | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-GOGO | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-GOGR | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-GRRE | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-GROR | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-GRGO | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-GRGR | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-AQRE | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-AQOR | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-AQGO | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-AQGR | 20 (40 μL) | 200 μL |
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| PRCC-RHBG-20-AQAQ | 20 (40 μL) | 200 μL |
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PRCC Gene Summary
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]
Gene Name: Papillary Renal Cell Carcinoma (translocation-associated)
Chromosome: CHR1: 156737273 -156770609
Locus: 1q23.1
RHBG Gene Summary
This gene encodes one of two non-erythroid members of the Rhesus (Rh) protein family. Non-erythroid Rh protein family members are mainly expressed in the kidney and belong to the methylammonium-ammonium permease/ammonia transporters superfamily. All Rh family proteins are predicted to be transmembrane proteins with 12 membrane spanning domains and intracytoplasmic N- and C-termini. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Name: Rh Family B Glycoprotein (gene/pseudogene)
Chromosome: CHR1: 156339002 -156355011
Locus: 1q22
Gene Diseases
The PRCC RHBG Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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