PPT1-HIVEP3 Fusion FISH Probe
The PPT1-HIVEP3 Fusion FISH Probe is used to confirm a fusion of the PPT1 and HIVEP3 genes. The fusion of the PPT1 and HIVEP3 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPT1-HIVEP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-RERE | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-REOR | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-REGO | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-REGR | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-REAQ | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-ORRE | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-OROR | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-ORGO | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-GORE | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-GOOR | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-GOGO | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-GOGR | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-GRRE | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-GROR | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-GRGO | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-GRGR | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-AQRE | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-AQOR | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-AQGO | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-AQGR | 20 (40 μL) | 200 μL |
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| PPT1-HIVEP3-20-AQAQ | 20 (40 μL) | 200 μL |
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PPT1 Gene Summary
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008]
Gene Name: Palmitoyl-protein Thioesterase 1
Chromosome: CHR1: 40538381 -40563142
Locus: 1p34.2
HIVEP3 Gene Summary
This gene encodes a member of the human immunodeficiency virus type 1 enhancer-binding protein family. Members of this protein family contain multiple zinc finger and acid-rich (ZAS) domains and serine-threonine rich regions. This protein acts as a transcription factor and is able to regulate nuclear factor kappaB-mediated transcription by binding the kappaB motif in target genes. This protein also binds the recombination signal sequence that flanks the V, D, and J regions of immunoglobulin and T-cell receptors. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Sep 2011]
Gene Name: Human Immunodeficiency Virus Type I Enhancer Binding Protein 3
Chromosome: CHR1: 41975683 -42384496
Locus: 1p34.2
Gene Diseases
The PPT1 HIVEP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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