PPP4R2-FOXP1 Fusion FISH Probe
The PPP4R2-FOXP1 Fusion FISH Probe is used to confirm a fusion of the PPP4R2 and FOXP1 genes. The fusion of the PPP4R2 and FOXP1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP4R2-FOXP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-RERE | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-REOR | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-REGO | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-REGR | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-OROR | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-GORE | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-GROR | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP4R2-FOXP1-20-AQAQ | 20 (40 μL) | 200 μL |
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FOXP1 Gene Summary
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box P1
Chromosome: CHR3: 71004735 -71633140
Locus: 3p13
PPP4R2 Gene Summary
The protein encoded by this gene is a regulatory subunit of the serine/threonine-protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Gene Name: Protein Phosphatase 4 Regulatory Subunit 2
Chromosome: CHR3: 73046118 -73115011
Locus: 3p13
Gene Diseases
The PPP4R2 FOXP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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