PPP4R1-NUP93 Fusion FISH Probe
The PPP4R1-NUP93 Fusion FISH Probe is used to confirm a fusion of the PPP4R1 and NUP93 genes. The fusion of the PPP4R1 and NUP93 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP4R1-NUP93-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-RERE | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-REOR | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-REGO | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-REGR | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-OROR | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-GORE | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-GROR | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP4R1-NUP93-20-AQAQ | 20 (40 μL) | 200 μL |
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NUP93 Gene Summary
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene encodes a nucleoporin protein that localizes both to the basket of the pore and to the nuclear entry of the central gated channel of the pore. The encoded protein is a target of caspase cysteine proteases that play a central role in programmed cell death by apoptosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Gene Name: Nucleoporin 93
Chromosome: CHR16: 56764016 -56878861
Locus: 16q13
PPP4R1 Gene Summary
This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Gene Name: Protein Phosphatase 4 Regulatory Subunit 1
Chromosome: CHR18: 9546791 -9614600
Locus: 18p11.22
Gene Diseases
The PPP4R1 NUP93 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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