PPP3CA-BRD2 Fusion FISH Probe
The PPP3CA-BRD2 Fusion FISH Probe is used to confirm a fusion of the PPP3CA and BRD2 genes. The fusion of the PPP3CA and BRD2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP3CA-BRD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-RERE | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-REOR | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-REGO | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-REGR | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-OROR | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-GORE | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-GROR | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP3CA-BRD2-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP3CA Gene Summary
The Protein Phosphatase 3 Catalytic Subunit Alpha (PPP3CA) gene is located on chr4 :101944586-102268628 at 4q24.
Gene Name: Protein Phosphatase 3 Catalytic Subunit Alpha
Chromosome: CHR4: 101944586 -102268628
Locus: 4q24
BRD2 Gene Summary
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Bromodomain Containing 2
Chromosome: CHR6_ssto_hap7: 4367204 -4430060
Locus: 6p21.32
Gene Diseases
The PPP3CA BRD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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