PPP2R5C-PRKD1 Fusion FISH Probe
The PPP2R5C-PRKD1 Fusion FISH Probe is used to confirm a fusion of the PPP2R5C and PRKD1 genes. The fusion of the PPP2R5C and PRKD1 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPP2R5C-PRKD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PPP2R5C-PRKD1-20-AQAQ | 20 (40 μL) | 200 μL |
|
PPP2R5C Gene Summary
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Protein Phosphatase 2 Regulatory Subunit B'gamma
Chromosome: CHR14: 102228134 -102394328
Locus: 14q32.31
PRKD1 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase involved in many cellular processes, including Golgi body membrane integrity and transport, cell migration and differentiation, MAPK8/JNK1 and Ras pathway signaling, MAPK1/3 (ERK1/2) pathway signaling, cell survival, and regulation of cell shape and adhesion. [provided by RefSeq, Jan 2017]
Gene Name: Protein Kinase D1
Chromosome: CHR14: 30045686 -30396899
Locus: 14q12
Gene Diseases
The PPP2R5C PRKD1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|