PPP2R2A-LGI3 Fusion FISH Probe
The PPP2R2A-LGI3 Fusion FISH Probe is used to confirm a fusion of the PPP2R2A and LGI3 genes. The fusion of the PPP2R2A and LGI3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP2R2A-LGI3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-RERE | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-REOR | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-REGO | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-REGR | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-OROR | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-GORE | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-GROR | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP2R2A-LGI3-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2R2A Gene Summary
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Gene Name: Protein Phosphatase 2 Regulatory Subunit Balpha
Chromosome: CHR8: 26149006 -26230195
Locus: 8p21.2
LGI3 Gene Summary
The Leucine Rich Repeat LGI Family Member 3 (LGI3) gene is located on chr8 :22004342-22014344 at 8p21.3.
Gene Name: Leucine Rich Repeat LGI Family Member 3
Chromosome: CHR8: 22004342 -22014344
Locus: 8p21.3
Gene Diseases
The PPP2R2A LGI3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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