PPP2R1B-ALG9 Fusion FISH Probe
The PPP2R1B-ALG9 Fusion FISH Probe is used to confirm a fusion of the PPP2R1B and ALG9 genes. The fusion of the PPP2R1B and ALG9 genes has been associated with Lung Adenocarcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP2R1B-ALG9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-RERE | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-REOR | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-REGO | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-REGR | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-OROR | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-GORE | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-GROR | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP2R1B-ALG9-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2R1B Gene Summary
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Gene Name: Protein Phosphatase 2 Scaffold Subunit Abeta
Chromosome: CHR11: 111597631 -111637169
Locus: 11q23.1
ALG9 Gene Summary
This gene encodes an alpha-1,2-mannosyltransferase enzyme that functions in lipid-linked oligosaccharide assembly. Mutations in this gene result in congenital disorder of glycosylation type Il. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: ALG9, Alpha-1,2-mannosyltransferase
Chromosome: CHR11: 111652918 -111742305
Locus: 11q23.1
Gene Diseases
The PPP2R1B ALG9 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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