PPP2R1A-CENPP Fusion FISH Probe
The PPP2R1A-CENPP Fusion FISH Probe is used to confirm a fusion of the PPP2R1A and CENPP genes. The fusion of the PPP2R1A and CENPP genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP2R1A-CENPP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-RERE | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-REOR | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-REGO | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-REGR | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-OROR | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-GORE | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-GROR | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP2R1A-CENPP-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2R1A Gene Summary
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Gene Name: Protein Phosphatase 2 Scaffold Subunit Aalpha
Chromosome: CHR19: 52693054 -52729678
Locus: 19q13.41
CENPP Gene Summary
CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008]
Gene Name: Centromere Protein P
Chromosome: CHR9: 95087740 -95377437
Locus: 9q22.31
Gene Diseases
The PPP2R1A CENPP Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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