PPP2CB-DLC1 Fusion FISH Probe
The PPP2CB-DLC1 Fusion FISH Probe is used to confirm a fusion of the PPP2CB and DLC1 genes. The fusion of the PPP2CB and DLC1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP2CB-DLC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-RERE | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-REOR | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-REGO | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-REGR | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-OROR | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-GORE | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-GROR | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP2CB-DLC1-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2CB Gene Summary
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010]
Gene Name: Protein Phosphatase 2 Catalytic Subunit Beta
Chromosome: CHR8: 30643125 -30670352
Locus: 8p12
DLC1 Gene Summary
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]
Gene Name: DLC1 Rho GTPase Activating Protein
Chromosome: CHR8: 12940871 -13372429
Locus: 8p22
Gene Diseases
The PPP2CB DLC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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