PPP2CA-CDKL3 Fusion FISH Probe
The PPP2CA-CDKL3 Fusion FISH Probe is used to confirm a fusion of the PPP2CA and CDKL3 genes. The fusion of the PPP2CA and CDKL3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPP2CA-CDKL3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PPP2CA-CDKL3-20-AQAQ | 20 (40 μL) | 200 μL |
|
PPP2CA Gene Summary
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008]
Gene Name: Protein Phosphatase 2 Catalytic Subunit Alpha
Chromosome: CHR5: 133532147 -133561950
Locus: 5q31.1
CDKL3 Gene Summary
The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Cyclin Dependent Kinase Like 3
Chromosome: CHR5: 133634114 -133702765
Locus: 5q31.1
Gene Diseases
The PPP2CA CDKL3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|