PPP1R9A-CYP3A43 Fusion FISH Probe
The PPP1R9A-CYP3A43 Fusion FISH Probe is used to confirm a fusion of the PPP1R9A and CYP3A43 genes. The fusion of the PPP1R9A and CYP3A43 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP1R9A-CYP3A43-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-RERE | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-REOR | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-REGO | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-REGR | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-OROR | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-GORE | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-GROR | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP1R9A-CYP3A43-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP1R9A Gene Summary
This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Name: Protein Phosphatase 1 Regulatory Subunit 9A
Chromosome: CHR7: 94536948 -94925727
Locus: 7q21.3
CYP3A43 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Gene Name: Cytochrome P450 Family 3 Subfamily A Member 43
Chromosome: CHR7: 99425635 -99464173
Locus: 7q22.1
Gene Diseases
The PPP1R9A CYP3A43 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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